EMIF-Platform Project Overview
EMIF has ultimately build an integrated, efficient Information Framework for consistent re-use and exploitation of available patient-level data to support novel research. This will support data discovery, data evaluation and then (re)use.
EMIF-Platform System Overview
EMIF-Platform has developed an IT platform allowing access to multiple, diverse data sources. The EMIF-Platform made this data available for browsing and allows exploitation in multiple ways by the end user. EMIF-Platform has leveraged data on more then 62 Million European adults and children by means of federation of healthcare databases and cohorts from 7 different countries (DK, IT, NL, UK, ES, EE), designed to be representative of the different types of existing data sources (population-based registries, hospital-based databases, cohorts, national registries, biobanks, etc.).
The EMIF Data Catalogue is now available outside of EMIF to bona fide researchers – more information via here.
EMIF Platform EHR Video
This video provides an overview of a service approach via EHR data post-IMI
EMIF Platform Cohort Video
This video provides an overview of a service approach via Cohort data post-IMI
To achieve EMIF-Platform objectives, the project was divided into eight work packages (WP9-WP16 below). In addition, there are four EMIF-AD work packages and four EMIF-MET work packages to explore.
- Key tool developed – EMIF Catalogue as data “shop window” to support the platform architecture, also being utilised by other initiatives (ADVACE, MOCHA, IMI-EPAD, DP-UK)
- Development & integration of TASKA in the EMIF catalogue to manage the workflow.
Common Data Model
EMIF: OMOP-CDM, OHDSI
- Mapped 10 European Databases to the OMOP-CDM
- Contributes to the extension of the CDM and Standardized Vocabularies to accommodate the European data
- Supports the European OHDSI initiative to stimulate adoption of the CDM and collaboration across Europe
- ATLAS tool developed by OHDSI is used to conduct scientific analyses on standardized health data
- EMIF is evaluating the OHDSI tools in the EMIF community and is actively contributing to their further development
- Raw cohort data integration and analysis via tranSMART and allied bioinformatics tooling development to support biomarker discovery in AD and metabolic disorders
- 3423 subjects from 14 AD cohorts harmonized
- Support of multi-omics data analysis.